diff --git a/tools/valgrind/MPICH.supp b/tools/valgrind/MPICH.supp
index 09a52472d9..01681974ac 100644
--- a/tools/valgrind/MPICH.supp
+++ b/tools/valgrind/MPICH.supp
@@ -121,6 +121,17 @@
    fun:PMPI_Init
    ...
 }
+{
+   MPICH_MPI_init10
+   Memcheck:Leak
+   match-leak-kinds: reachable
+   fun:malloc
+   ...
+   fun:MPII_Init_thread.isra.0
+   ...
+   fun:PMPI_Init
+   ...
+}
 {
    MPICH_library1
    Memcheck:Leak
@@ -128,14 +139,6 @@
    fun:malloc
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
-   ...
-   fun:Run
-   fun:*
-   fun:*
-   fun:Run
    ...
 }
 {
@@ -147,9 +150,6 @@
    fun:MPIDI_OFI_init_local
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
    ...
 }
 {
@@ -164,9 +164,6 @@
    fun:MPIR_init_comm_world
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
    ...
 }
 {
@@ -180,9 +177,6 @@
    fun:hwloc_topology_load
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
    ...
 }
 {
@@ -208,13 +202,7 @@
    fun:MPIR_init_comm_world
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
    ...
-   fun:Run
-   fun:*
-   fun:*
 }
 {
    MPICH_comm2
@@ -228,13 +216,7 @@
    fun:MPIR_init_comm_world
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
    ...
-   fun:Run
-   fun:*
-   fun:*
 }
 {
    MPICH_comm3
@@ -248,13 +230,7 @@
    fun:MPIR_init_comm_self
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
    ...
-   fun:Run
-   fun:*
-   fun:*
 }
 {
    MPICH_comm4
@@ -268,13 +244,7 @@
    fun:MPIR_init_comm_self
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
    ...
-   fun:Run
-   fun:*
-   fun:*
 }
 {
    MPICH_psm3_1
@@ -307,8 +277,7 @@
    fun:MPIDI_OFI_init_local
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
+   ...
 }
 {
    MPICH_psm3_3
@@ -344,8 +313,7 @@
    fun:MPIDI_OFI_init_local
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
+   ...
 }
 {
    MPICH_hwloc1
@@ -362,9 +330,7 @@
    fun:hwloc_topology_load
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
+   ...
 }
 {
    MPICH_hwloc2
@@ -379,10 +345,16 @@
    fun:hwloc_topology_load
    ...
    fun:PMPI_Init
-   fun:lammps_mpi_init
-   fun:lammps_mpi_init
-   fun:lammps_open
-   fun:*
-   fun:*
-   fun:*
+   ...
+}
+{
+   MPICH_hwloc3
+   Memcheck:Leak
+   match-leak-kinds: reachable
+   fun:malloc
+   fun:*
+   fun:hwloc__topology_init
+   ...
+   fun:PMPI_Init
+   ...
 }
diff --git a/tools/valgrind/Python3.supp b/tools/valgrind/Python3.supp
index 2e455c8db4..26350ab9c1 100644
--- a/tools/valgrind/Python3.supp
+++ b/tools/valgrind/Python3.supp
@@ -143,3 +143,165 @@
   fun:PyUnicode_FromKindAndData
   ...
 }
+{
+  Python3_init_1
+  Memcheck:Leak
+  match-leak-kinds: reachable
+  fun:malloc
+  ...
+  fun:PyMem_Malloc
+  fun:PyModule_ExecDef
+  ...
+  fun:pycore_interp_init
+  ...
+  fun:Py_InitializeFromConfig
+  ...
+}
+{
+  Python3_init_2
+  Memcheck:Leak
+  match-leak-kinds: reachable
+  fun:realloc
+  fun:_Py_EncodeUTF8Ex
+  fun:encode_wstr_utf8
+  ...
+  fun:py_interp_main
+  fun:pyinit_main
+  fun:Py_InitializeFromConfig
+  ...
+}
+{
+  Python3_init_3
+  Memcheck:Leak
+  match-leak-kinds: reachable
+  fun:malloc
+  fun:_PyMem_RawStrdup
+  ...
+  fun:py_interp_main
+  fun:pyinit_main
+  fun:Py_InitializeFromConfig
+  ...
+}
+{
+  Python3_init_4
+  Memcheck:Leak
+  match-leak-kinds: reachable
+  fun:malloc
+  fun:*
+  fun:_extensions_cache_find_unlocked
+  ...
+  fun:_PyImport_FixupBuiltin
+  fun:_PySys_Create
+  fun:pycore_interp_init
+  ...
+  fun:Py_InitializeFromConfig
+  ...
+}
+{
+  Python3_init_5
+  Memcheck:Leak
+  match-leak-kinds: possible
+  fun:calloc
+  ...
+  fun:PyMem_Calloc
+  fun:PyList_New
+  fun:_PyWideStringList_AsList
+  fun:*
+  fun:interpreter_update_config
+  fun:init_interp_main
+  fun:pyinit_main
+  fun:Py_InitializeFromConfig
+  ...
+}
+{
+  Python3_init_6
+  Memcheck:Leak
+  match-leak-kinds: possible
+  fun:calloc
+  ...
+  fun:PyMem_Calloc
+  fun:PyList_New
+  fun:*
+  fun:_PyEval_EvalFrameDefault
+  ...
+  fun:PyObject_CallFunction
+  fun:PyImport_Import
+  fun:PyImport_ImportModule
+  ...
+  fun:init_interp_main
+}
+{
+  Python3_init_7
+  Memcheck:Leak
+  match-leak-kinds: possible
+  fun:calloc
+  ...
+  fun:PyMem_Calloc
+  fun:PyList_New
+  fun:*
+  fun:_PyEval_EvalFrameDefault
+  fun:PyEval_EvalCode
+  ...
+  fun:PyObject_CallFunction
+  fun:PyImport_Import
+  fun:PyImport_ImportModule
+  ...
+}
+{
+  Python3_init_8
+  Memcheck:Leak
+  match-leak-kinds: possible
+  fun:calloc
+  ...
+  fun:PyMem_Calloc
+  fun:PyList_New
+  fun:*
+  fun:_PyEval_EvalFrameDefault
+  fun:*
+  fun:object_vacall
+  fun:PyObject_CallMethodObjArgs
+  ...
+  fun:_PyEval_EvalFrameDefault
+  fun:*
+  fun:object_vacall
+  fun:PyObject_CallMethodObjArgs
+  fun:*
+  fun:PyImport_ImportModuleLevelObject
+}
+{
+  Python3_init_9
+  Memcheck:Leak
+  match-leak-kinds: possible
+  fun:calloc
+  ...
+  fun:PyMem_Calloc
+  fun:PyList_New
+  fun:*
+  fun:_PyEval_EvalFrameDefault
+  fun:*
+  fun:object_vacall
+  fun:PyObject_CallMethodObjArgs
+  ...
+  fun:_PyEval_EvalFrameDefault
+  fun:PyEval_EvalCode
+  ...
+}
+{
+  Python3_init_10
+  Memcheck:Leak
+  match-leak-kinds: possible
+  fun:calloc
+  ...
+  fun:PyMem_Calloc
+  fun:PyList_New
+  fun:*
+  fun:_PyEval_EvalFrameDefault
+  ...
+  fun:PyObject_Vectorcall
+  fun:_PyEval_EvalFrameDefault
+  fun:PyEval_EvalCode
+  fun:*
+  fun:builtin_exec
+  ...
+  fun:_PyEval_EvalFrameDefault
+}
diff --git a/tools/valgrind/libc.supp b/tools/valgrind/libc.supp
index 2b90fd3f1f..a5942c8ed5 100644
--- a/tools/valgrind/libc.supp
+++ b/tools/valgrind/libc.supp
@@ -67,3 +67,16 @@
    fun:_dl_catch_exception
    fun:_dl_catch_error
 }
+{
+   libc_dlclose1
+   Memcheck:Leak
+   match-leak-kinds: reachable
+   fun:malloc
+   fun:*
+   fun:_dl_close_worker
+   fun:_dl_close
+   fun:_dl_catch_exception
+   fun:_dl_catch_error
+   fun:_dlerror_run
+   ...
+}