diff --git a/src/USER-INTEL/fix_intel.cpp b/src/USER-INTEL/fix_intel.cpp
index 3e36c8f7a9..cac5e0b49c 100644
--- a/src/USER-INTEL/fix_intel.cpp
+++ b/src/USER-INTEL/fix_intel.cpp
@@ -34,6 +34,10 @@
 #include <stdio.h>
 #include <math.h>
 
+#ifdef LAMMPS_BIGBIG
+#error "The USER-INTEL package is not compatible with -DLAMMPS_BIGBIG"
+#endif
+
 #ifdef _LMP_INTEL_OFFLOAD
 #ifndef INTEL_OFFLOAD_NOAFFINITY
 #include <unistd.h>